Opinion - African Journal of Diabetes medicine (2023)

The crucial role of basal insulin therapy in diabetes management
Department of Medicine, University of Colorado School of Medicine, USA

*Corresponding Author:

Brenda Ross, Department of Medicine, University of Colorado School of Medicine, USA, Email: brendaross@ll.edu

Received: 01-Aug-2023, Manuscript No. ajdm-23-115950 ; Editor assigned: 03-Aug-2023, Pre QC No. ajdm-23-115950 (PQ) ; Reviewed: 17-Aug-2023, QC No. ajdm-23-115950 ; Revised: 22-Aug-2023, Manuscript No. ajdm-23-115950 (R) ; Published: 29-Aug-2023, DOI: 10.54931/AJDM-31.4.2.


Diabetes is a chronic condition that affects millions of people worldwide, and its effective management is essential to prevent complications. Basal insulin therapy is a fundamental component of diabetes care, particularly for individuals with type 1 diabetes and some with type 2 diabetes. In this article, we will explore what basal insulin therapy is, how it works, and its significance in diabetes management. Insulin acts as a key to unlock cells, allowing glucose to enter and be used for energy. Basal insulin is a type of insulin that provides a steady, background level of insulin throughout the day and night, regardless of meals.


Basal insulin therapy is primarily used in two main groups of people with diabetes: Individuals with type 1 diabetes have a complete lack of insulin production in their bodies. Therefore, they require both basal and bolus insulin therapy to mimic the natural insulin secretion that occurs in those without diabetes. Some people with type 2 diabetes, especially those with advanced or long-standing disease, may also benefit from basal insulin therapy. This is often necessary when oral medications or other injectable medications are no longer sufficient to control blood sugar levels. Basal insulin is designed to mimic the constant release of insulin that a healthy pancreas provides. Inhibit the liver from producing excess glucose, reducing the liver’s contribution to high blood sugar levels. Counteract the body’s natural release of glucose during fasting periods, such as overnight. Maintain a consistent background level of insulin to prevent dangerous spikes or drops in blood sugar. Insulin glargine and insulin detemir are examples of long-acting insulin analogs. They provide a relatively steady level of insulin for up to 24 hours, requiring one daily injection. Insulin NPH is an older form of basal insulin that provides a consistent background level of insulin but may have a slightly less predictable duration of action. Basal insulin therapy plays a critical role in diabetes management for several reasons. It helps maintain stable blood sugar levels, reducing the risk of both hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). Effective blood sugar control with basal insulin helps prevent long-term complications of diabetes, such as heart disease, kidney disease, and neuropathy. Stable blood sugar levels contribute to an improved quality of life by reducing the physical and emotional toll of diabetes-related fluctuations. Basal insulin therapy provides flexibility in meal timing and dietary choices, as it keeps blood sugar levels stable between meals and overnight.


Basal insulin therapy is a cornerstone of diabetes management for individuals with type 1 diabetes and some with type 2 diabetes. It offers stability, reduces the risk of complications, and enhances the overall quality of life for those living with diabetes. However, diabetes management is highly individualized, and healthcare providers work closely with patients to determine the most appropriate insulin regimen and lifestyle adjustments to achieve optimal blood sugar control. With the right approach, individuals with diabetes can effectively manage their condition and lead healthy, fulfilling lives. In addition to its core role in maintaining blood sugar stability, basal insulin therapy has evolved over the years with the introduction of insulin analogs, offering even greater precision and convenience.

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