This study aimed to determine the blood glucose profle in acutely ill children admitted to a paediatric ward and to evaluate the prognosis of the association between hypoglycaemia (blood glucose < 3.3 mmol/l) or hyperglycaemia (blood glucose ≥ 6.9 mmol/l) and disease condition. A cross-sectional descriptive study was conducted from 16th June 2014 to 16th December 2014 in Abobo North General Hospital in Abidjan. Five hundred and two (502) children aged one month to ffteen years were recruited. Random capillary blood glucose (BG) level was measured in all children using a glucometer Accu-chek Active. Data were analysed by the use of STATA 13 and the Chi-square test was used for proportions analysis. The prevalence rate of hypoglycaemia and hyperglycaemia were respectively 9 and 11%. These blood glucose abnormalities in acutely ill children occurred in various disease conditions and were most common in children under fve years – 4.8 % had severe hypoglycaemia (BG >2.2mmol/l) while 11.7 % had hyperglycaemia with 3.3 % reaching a BG >10 mmol/l. In hypoglycaemia, the BG levels ranged from 0.6 to 3.2 mmol/l and were most common in children aged less than fve years. The mortality of children who presented on admission with a blood glucose abnormality was 4.0%. We recommend routine determination of BG levels, which may help decrease mortality linked to abnormal levels in ill children admitted to pediatric wards

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